Informative blog articles about CBD


CBDA? Is that perhaps a new, improved form of CBD? No, listen, CBDA is the natural precursor of CBD as it occurs in the plant. Because we sell products that specifically contain CBDA, it’s important for you to know what the differences are between CBD and CBDA.


CBD is ‘Made’.

Did you know that C.B.D hardly occurs in hemp or weed? Don’t panic – we’re not suggesting that C.B.D is a synthetic product which is added to oil. C.B.D is actually a completely natural substance that is formed in the cannabis plant under the influence of several factors.

One of these factors is heat. To get a good understanding of where C.B.D comes from we can take a look into the factory where C.B.D oil is made. Why not come with us?

How Is CBD Oil Made?

C.B.D oil is made from sun-ripened hemp fibre. That’s the short answer. But that’s similar to saying that an aircraft is made from aluminium – it’s just a small part of a complex story.

Keeping it simple, there are three important phases in the production of C.B.D oil:

  1. Extraction
  2. Decarboxylation (heating)
  3. Diluting

Extraction is nothing more than getting the required substances out of the plant material. CO2 extraction is by far the most common method and this uses no solvents.


Met geavanceerde apparatuur worden de cannabinoïden uit de hennep geëxtraheerd.

What’s interesting to realize is that there is very little C.B.D in extracted hemp fiber. That’s because the C.B.D is, so to speak, ‘locked-in’. We can find all kinds of other cannabinoids. They are part of a family of natural substances which we find in hemp and weed, among others. C.B.D is also one of these.

Decarboxylation of CBDA

One of the relatively frequently occurring cannabinoids in cannabis is CBDA. That is the abbreviation for cannabidiol acid. In this brief chemistry lesson, we will strip the ‘A’ from the C.B.D. In the factory, they do that by heating the hemp extract very accurately. The result is that virtually all the CBDA is converted into C.B.D!

The final step is to dilute with a plant-derived base oil, because the hemp extract is really thick, concentrated and, furthermore, difficult to dose. Hemp seed oil is commonly used for this purpose. This is made from cold-pressed hemp seeds.

What is CBDA?

You can therefore look upon C.B.D as the grown-up version of CBDA. But some studies suggest that CBDA is just valuable for us as C.B.D. Only they work slightly differently. C.B.D and most other cannabinoids latch on to the CB1 and CB2 receptors in our bodies. These are tiny receptors onto which both our body’s own substances as well as external ones like C.B.D fit very precisely.

CBDA does not work in this way. Instead of that, CBDA initiates a reaction with our body by inhibiting the cyclooxygenase-2 (COX-2) enzyme. There is a connection between COX-2 enzymes and inflammation after an injury or infection. Thus CBDA is able to reduce the inflammation and the pain it causes by blocking this enzyme.

Furthermore, it seems that CBDA is much better able to attach to the 5-HT receptor, to which our hormone serotonin also attaches. There are therefore indications that CBDA has both an anti-convulsive (helps relieve nausea) and an antidepressant effect.

But we have to admit that further investigation is needed into the findings of these studies. For that reason, it is definitely not a good idea to stop taking your regular medication. Always consult your doctor or treating specialist therefore if you are interested in the medicinal application of CBDA.


The chemical formula of CBDA. The only difference from C.B.D is the ‘COOH’ bit. Remove that line and what’s left is C.B.D. And that’s done by very accurate heating.


The first results are in any case very interesting. For just that reason, there are almost as many CBDA products on the market as there are products with C.BD. Take, for example, C.BD Oil Raw from Medihemp. ‘Raw’ oil contains CBDA and other natural substances in addition to CB.D.

That’s the case because Raw CBD oil has never been heated. A stage in the production is ‘omitted’. As a result, a Raw extract preserves all constituents of the hemp plant. And that, in turn, does something to the taste. The aroma of a Raw CB.D oil is often fuller. Strongly nutty and fairly bitter.

At Medihemp, the heated oil is referred to as ‘Pure’. The heating causes all CBDA to be converted into C.BD and some volatile substances are evaporated. Consequently, the sharp edge to the taste of C.BD oil is taken off, making products like C.BD Oil Pure milder on the tongue.

C.BD Oil Raw contains C.BDA as well as C.BD. CB.D Oil Pure is milder in taste.

CBDA BoostersSpecial CB.DA products are the CB.DA boosters from Sana Hemp Juice. These capsules contain a Raw extract from hemp in which as much CB.DA is preserved as possible. The unique orodispersible tablets from Sana Hemp Juice have a fresh, acidic taste. A bit like an acid drop. One tablet contains 5 milligrams of C.BDA.


Perhaps we might compare the importance of heating or applying decarboxylation with the example of THC. THC, the psychoactive ingredient in weed, occurs in nature only in the acidic form of THCA. And THCA is not psychoactive. If weed is not heated, you don’t get high or stoned from it. For that reason, weed is often smoked or vaped – to convert the THCA into THC and get the effect.

Just to be clear: THC and THCA are not present in approved C.BD oil. C.BD oil is made from hemp which doesn’t contain either THC or THCA. You cannot therefore get high or stoned from C.BD oil in our range.

CBGNo story about C.BD production would be complete without mentioning CBG as well. CBG is naturally present in hemp and weed as the precursor or building block of both C.BDA and THCA. Although it’s still early days in the development of CBG products, Medihemp has already brought out a wonderful organic CBG oil on the market.


A pure hemp extract.

Nuance and NatureWe wrote earlier that C.BD hardly occurs in nature. The emphasis lies on ‘hardly’. If the hemp flowers are exposed all day to the burning sun, then some C.BD will occur. And that applies to weed flowers also. If the temperature in August gets up towards 40 degrees, a small amount of conversion is inevitable.

The nature of hemp is fascinating. The plants themselves are tiny factories of all kinds of natural substances. We trust that this article has turned you into a bit more of an Expert when it comes to C.BD.



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